Refractory Gastroesophageal Reflux

Refractory Gastroesophageal Reflux

Refractory Gastroesophageal Reflux Despite treatment with proton pump inhibitors (PPIs), some patients with gastroesophageal reflux disease (GERD) continue to have reflux symptoms or endoscopic evidence of esophagitis. Approximately 10 and 40 percent of patients with GERD fail to respond symptomatically, either partially or completely, to a standard dose PPI [1-4]. Failure of the PPI treatment to resolve GERD-related symptoms has…

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IMPACT OF MONITORING FOR MUCOSAL INFLAMMATION AFTER BIOLOGIC INITIATION IN INFLAMMATORY BOWEL DISEASE

IMPACT OF MONITORING FOR MUCOSAL INFLAMMATION AFTER BIOLOGIC INITIATION IN INFLAMMATORY BOWEL DISEASE

By Oxford Academic. Berkeley N Limketkai, MD, PhD Siddharth Singh, MD Vipul Jairath, MD, PhD William J Sandborn, MD Parambir S Dulai, MD. Abstract Background We assessed practice patterns for monitoring mucosal inflammation after biologic initiation and the association between monitoring approaches and development of disease-related complications for Crohn’s disease (CD) and ulcerative colitis (UC). Methods This study used a…

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THE GUT-BRAIN CONNECTION

THE GUT-BRAIN CONNECTION

Pay attention to your gut-brain connection – it may contribute to your anxiety and digestion problems The gut-brain connection is no joke; it can link anxiety to stomach problems and vice versa. Have you ever had a “gut-wrenching” experience? Do certain situations make you “feel nauseous”? Have you ever felt “butterflies” in your stomach? We use these expressions for a…

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THERE’S NO SUCH THING AS A ONE-SIZE-FITS ALL DIET

THERE’S NO SUCH THING AS A ONE-SIZE-FITS ALL DIET

Though they’re not without critics, the U.S. federal dietary guidelines have for years aimed to give all Americans a blueprint for good nutrition. But new research says this kind of one-size-fits-all approach may not cut it. Different people, even identical twins (who have nearly the exact same DNA), may respond to the same foods very differently, the researchers found—complicating decades…

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